The Owen Hugh Graham Papers relate to screwworm eradication efforts in Florida, the Southwestern United States, Mexico, Central America, and North Africa. Materials include correspondence, reports, publications, maps, charts, photographs, public information materials, and manuscripts. The language of materials is mostly English, with some items in Spanish and a few articles in French.

The Screwworm Eradication Program Audiovisual Materials include photographs, slides, and films portraying screwworm eradication efforts in the United States, Mexico, and South America.

The Screwworm Eradication Program Promotional Materials include items relating to screwworm eradication programs in the Southwestern United States, Mexico, Central America, and North Africa. There are public information and promotional materials such as baseball caps, mugs, calendars, key rings, bumper stickers, publications and brochures, photographs, fly case collection reports, 16-millimeter films, and fly distribution artifacts.